In Boston, on December 11, 2024, Dr. Bin Wu, Cytodigm’s Founder and CEO, will present “Case Study: Building Next-Generation LNPs with Gangliosides Instead of PEG to Reinvent Safety and Mitigate Immunogenicity.”
Introduction
With the applications of LNPs rapidly expanding beyond vaccines, as well as beyond the liver, it is of utmost importance to predict and minimize adverse reactions to guarantee patient safety in the clinic, especially following a clinical hold on Verve Therapeutics’ gene therapy earlier this year, due to safety concerns surrounding the LNP delivery system.
Returning in December, the 3rd LNP Immunogenicity and Toxicity Summit will return as your unique forum uniting industry experts striving to measure, predict and monitor non-clinical and clinical safety risk for lipid nanoparticles to ensure regulatory compliance for vaccines, gene and cell therapies.
Join experts from Pfizer, AstraZeneca, Moderna, BioNTech and Beam Therapeutics, as they dive deep into mechanisms of toxicity, optimal delivery strategy, PEG-lipid alternatives and in vitro prediction, to progress development of safer LNP-delivered therapeutics.
